A self-adjuvanting anti-tumor nanoliposomal vaccine based on fluorine-substituted MUC1 glycopeptide

Peijie Dong, Suying Cheng, Yudie Wang,Hang Gao,Yongmin Zhang,Tao Zhu,Peng Yu,Xin Meng

CHEMICAL COMMUNICATIONS（2022）

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摘要

Herein, a self-adjuvanting fluorinated MUC1-based nanoliposomal antitumor vaccine was constructed for the first time. Both the tumor-associated antigen and the mode of its presentation affect the immune response for antitumor vaccines.

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