Comprehensive evaluation of patterns of hypoglycemia unawareness (HUA) and glycemic variability (GV) in patients with fibrocalculous pancreatic diabetes (FCPD): A cross-sectional study from South India.

Riddhi Dasgupta,Felix K Jebasingh,Shajith Anoop, Santhya Seenivasan,Mathews Edatharayil Kurian,Flory Christina, Gracy Varghese,Pamela Christudoss, K U Lijesh,Deepu David,Sudipta Dhar Chowdhury,Thomas V Paul,Nihal Thomas

PloS one（2022）

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摘要

Heterogeneity in patterns of glucagon secretion were significantly associated with HUA and GV. Reduced glucagon levels contribute to greater risks of HUA, nocturnal hypoglycemia and greater GV, while hyperglucagonemia predisposes to postprandial hyperglycemia and hypoglycemia awareness in patients with FCPD.

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