Triclosan-induced Oxidative Stress Injury and Apoptosis by Regulating the PI3K/Akt/Caspase-3 Signaling Pathway in Human Renal Glomerular Endothelial Cells
Biomedical and Environmental Sciences(2022)
摘要
Triclosan (TCS) is widely used in personal-care products because of its bactericidal and antibacterial properties. However, TCS and its toxic byproducts have been detected in aquatic environments, animals, and plants worldwide. TCS is a common phenolic environmental endocrine disruptor, and TCS in the environment enters the body mainly through diet and water. Most of the absorbed TCS is metabolized by the human kidneys and is eliminated in the urine[1].
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