LncRNA LINC00680 Acts as a Competing Endogenous RNA and Is Associated With the Severity of Myasthennia Gravis.

Li Liu,Huixue Zhang,Xiaoyu Lu,Lifang Li,Tianfeng Wang,Shuang Li,Xu Wang,Si Xu,Lei Li,Qian Li,Tingting Yi, Tao Wu,Zhimin Chen,Hongyu Gao,Jianjian Wang,Lihua Wang

Frontiers in neurology（2022）

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摘要

LINC00680 may be associated with the severity of MG as a ceRNA by sponging miR-320a to upregulate MAPK1. These findings suggest that LINC00680 may represent a potential biomarker which evaluates the severity of MG and may serve as a therapeutic target.

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关键词

LINC00680,biomarker,competing endogenous RNA (ceRNA),myasthenia gravis,severity

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