Multiscale agent-based modeling of restenosis after percutaneous transluminal angioplasty: Effects of tissue damage and hemodynamics on cellular activity

•Multiscale agent-based modeling of femoral artery restenosis after angioplasty.•Fully automated integration of structural mechanics, CFD and agent-based models.•Arterial wall response to PTA-induced damage and hemodynamics post-intervention.•The local intimal growth, with regions of focal re-narrowing, was captured.•The lumen area temporal trend, featuring different restenosis phases, was captured.