Synthesis and Characterization of a Bifunctional Platform Based on Magnetite–Gold Nanoparticles for Theranostics of Cancer

Iuliia Chudosai, Marina Sorokina,Maxim Abakumov,Natalia Klyachko

Materials Proceedings(2023)

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摘要
One of the most interesting objects in terms of use in biomedicine are hybrid structures based on magnetic nanoparticles (NPs) and NPs of noble metals, which make it possible to simultaneously introduce two types of ligands onto the surface of NPs for their further use for photodynamic cancer therapy (PDT) (a combination of a photosensitizer (PS) for therapy and a fluorophore (FP) for platform detection). The synthesis and research of Fe3O4-Au NPs with a “dumbbell” structure as the bifunctional platform for the therapy of oncological diseases was the purpose of this work.
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关键词
nanomaterials,targeted therapy,magnetite,PDT,photosensitizer,fluorophore
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