IN VITRO HYDROXYAPATITE FORMING ABILITY OF DICALCIUM SILICATE PREPARED FROM LOCAL RAW MATERIALS AND SINTERED AT 1050?C

Ceramics - Silikaty(2022)

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摘要
In this study, Ca2SiO4 powders were synthesised using solid state reaction. The starting powders were sintered at 1050 ??C for 2 h. Moreover, the in vitro bioactivity of ??-Ca2SiO4 was investigated by soaking the powders in a simulated body fluid (SBF) for various time periods to analyse the growth of hydroxyapatite (HA) on the surface of these powders. The synthesised powders were characterised by scanning electron microscopy (SEM), X-ray diffraction (XRD), Fourier transform infrared (FTIR), and Inductively Coupled Plasma-Optical Emission Spectroscopy (ICP-OES) analysis. The simulated body fluid results showed that the ??-Ca2SiO4 powders had good bioactivity to induce hydroxyapatite formation on their surface. The results obtained showed that (HCA) can be formed on the surface of ??-Ca2SiO4 soaked in the SBF solution for 1 day, and a continuous layer of dense HCA deposits covered the surface of ??-Ca2SiO4 powders after 3 days of soaking in the SBF solution. Finally, the results obtained suggest that ??-Ca2SiO4 ceramics are promising candidates for bone regeneration.
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关键词
Bioceramics, In vitro tests, Bioactivity, Simulated body fluid
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