A multilayered nanofibrous patch functionalized with adipose tissue extract for the treatment of bladder regeneration

Jing Wang,Chunxiang Feng,Yunpeng Zhu,Zhixian Wang,Xiang Ren,Xing Li, Yisheng Ying,Yiqun Tian,Kai Yu,Shiliang Liu,Chang Liu,Xiaoyong Zeng

Materials & Design（2022）

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摘要

•ATE, a complex of various cytokines, could promote angiogenesis and maintain stem cell pluripotency.•We integrates PLCL electrospun microfibers and ATE/HA colloidal solution to constitute a hierarchical nanofibrous patch.•The patches could achieve the bionic reconstruction by providing a stable mechanical microenvironment and important biochemical factors.

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关键词

Tissue engineering,Bladder regeneration,Adipose tissue extract,Electrospinning,Angiogenesis

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