Omitting Radiotherapy in Luminal A Breast Cancer

To the Editor: The results of the LUMINA trial by Whelan et al. (Aug. 17 issue)(1) add substantially to our understanding regarding which postmenopausal patients with early-stage breast cancer can safely avoid radiation therapy after lumpectomy. However, few studies have shown how age at diagnosis affects this risk. The risk of local recurrence was similar among patients defined according to age groups of 50 to 60 years of age, 60 to 70 years of age, and older than 70 years of age in a study from London(2) and 60 to 69 years of age and 70 years of age or . . .