QOPI Clinical Informatics: A digital platform to enable real-time quality reporting, clinical decision support, and rapid learning.

e13545 Background: The ASCO Quality Oncology Practice Initiative (QOPI) was established in 2006 to facilitate quality measurement and continuous improvement of cancer care.1 ASCO and QOPI leadership encourage a continuous learning environment to develop new tools and methodologies that improve quality and maximize outcomes and value in oncology practice.2 Parallel advances in tumor molecular profiling, bioinformatics, and EMR data curation are adding new insights to support the real-world research of longitudinal patient journeys. Methods: Referencing the QOPI Certification Track 2021 Measures Summary, we employed data visualization techniques to create a precision oncology dashboard for breast cancer. This evaluation included 409 breast cancer patients for whom genomic testing was performed and presented at the Avera molecular tumor board. Patients were then matched to appropriate biomarker-based targeted therapies. Results: The dashboard identified and prioritized areas for enhanced data capture to inform strategies for care-coordination, research, and delivery of specialized care. Conclusions: An interactive, visual platform may help facilitate the integration of QOPI reporting into CancerLinQ, thereby fostering a real-time, bidirectional system for quality reporting, clinical decision support, and rapid learning.3,4 The next stage will (1) expand the tumor list; and (2) apply NLP methods to assess accuracy, outcomes and temporal reasoning to create interactive graphs for patient referral patterns and surgery decision drivers. References: 1. Neuss MN, Desch CE, McNiff KK, et al: A process for measuring the quality of cancer care: The Quality Oncology Practice Initiative. J Clin Oncol. 2005 2. Blayney DW, McNiff K, Eisenberg PD, Gilmore T, Jacobsen PB, Jacobson JO, Kadlubek PJ, Neuss MN, Simone J. Development and future of the American Society of Clinical Oncology's Quality Oncology Practice Initiative. J Clin Oncol. 2014 3. Blayney DW: Enhancing quality through innovation: American Society of Clinical Oncology presidential address 2010. J Clin Oncol. 2010 4. Schilsky R, Hauser R, Mann J, et al: Lessons learned from the development of the CancerLinQ prototype: Clinical decision support. J Clin Oncol. 31, 2013[Table: see text]