Proteogenomic characterization of cholangiocarcinoma.

Mengjie Deng,Peng Ran,Lingli Chen,Yunzhi Wang,Zixiang Yu,Ke Cai,Jinwen Feng,Zhaoyu Qin,Yanan Yin,Subei Tan,Yang Liu,Chen Xu,Guoming Shi,Yuan Ji,Jian-Yuan Zhao,Jian Zhou,Jia Fan,Yingyong Hou,Chen Ding

Hepatology (Baltimore, Md.)（2023）

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摘要

We characterized the proteogenomic landscape of 217 CCAs with 197 paired normal adjacent tissues and identified their subtypes and potential therapeutic targets. The multiomics analyses with other databases and some functional validations have indicated strategies regarding the clinical, biological, and therapeutic approaches to the management of CCA.

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cholangiocarcinoma,proteogenomic characterization

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