Malaria Transmission Dynamics in a High-Transmission Setting of Western Kenya and the Inadequate Treatment Response to Artemether-Lumefantrine in an Asymptomatic Population.

Ben Andagalu,Oliver J Watson,Irene Onyango,Benjamin Opot,Raphael Okoth,Gladys Chemwor,Peter Sifuna,Dennis Juma,Agnes Cheruiyot,Redemptah Yeda,Charles Okudo,Jackline Wafubwa,Santos Yalwala,David Abuom,Bernhards Ogutu,Jessica Cowden,Hoseah M Akala,Edwin Kamau

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America（2023）

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摘要

Individuals with asymptomatic infection sustain the transmission cycle, with the 6-11-year age group serving as an important reservoir. The high rates of artemether-lumefantrine treatment failures suggest surveillance programs using molecular methods need to be expanded for accurate monitoring and evaluation of treatment outcomes.

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关键词

Plasmodium falciparum ,artemether/lumefantrine,drug resistance,malaria control and elimination,malaria surveillance and transmission dynnamics

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