Control of ticks on horses using abamectin-impregnated ear tags. A pharmacokinetic and pharmacodynamic study.

JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS(2022)

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摘要
Several different tick species are known to infest horses. Aside from causing serious health and welfare issues, including anaemia, ill thrift, and immunosuppression, ticks can transmit a variety of important, sometimes zoonotic, pathogens. The successful prevention and treatment of tick infestations have been described, but the information is scarce and, in many instances, anecdotal. Here we describe a practical and affordable prevention of tick infestation by using abamectin-impregnated cattle ear tags affixed to a safety collar. We have assessed the radial distribution of abamectin by analyzing hair samples, as well as its efficacy against tick infestations. The study results show that abamectin distributes across horse skin from the site of application and its associated effectiveness in reducing the tick burden.
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关键词
abamectin, horse, pharmacokinetics, skin, ticks
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