N-cystaminylbiguanide MC001 prevents neuron cell death and alleviates motor deficits in the MPTP-model of Parkinson’s disease

•N-cystaminylbiguanide prevents cell death of TH-positive neurons and alleviates motor deficits.•N-cystaminylbiguanide promotes GSH synthesis by activating Gcl.•N-cystaminylbiguanide shows Anti-ROS and anti-inflammatory properties.•N-cystaminylbiguanide regulates the expression of BDNF in brain.