SPECT Imaging of Acute Disc Herniation by Targeting Integrin α5β1 in Rat Models.

Jian Guan,Chenghua Yuan, Xin Tian,Lei Cheng,Hannan Gao,Qingyu Yao,Xinyu Wang,Hao Wu,Zan Chen,Fengzeng Jian

Frontiers in neurology（2022）

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摘要

The present study demonstrated a good correlation between integrin α5β1 expression and acute disc herniation. The SPECT/CT imaging of Tc-3PisoDGR2 targeting integrin α5β1 may diagnose IVDH in an acute phase for early disease management.

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关键词

99mTc-3PisoDGR2,acute,disc herniation,integrin α5β1,molecular imaging

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