135P Real-time genotyping-based breast cancer risk assessment in MyPeBS, an international randomized trial in the general population comparing risk-stratified to standard breast cancer screening (BCS)

S. Delaloge, P. Giorgi Rossi, C. Balleyguier, M. Guindy,F.J. Gilbert, J-B. Burrion, M. Roman, S. de Montgolfier, L. Giordano,D. Drubay,D.G. Evans, D. Keatley, E. Gauthier, A. du Bois d'Aische, C. Baron, A. Boland, H. Blanché,D. Couch,J-F. Deleuze,S. Michiels

Annals of Oncology（2022）

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摘要

Risk-stratified BCS, integrating personal, familial variables and a polygenic risk score (PRS) is a promising strategy that may improve current BCS outcomes. Real-time risk assessment and field implementation are some of the main challenges for such an approach.

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