A membrane ATPase without transporter activity

Had he been a trifle less modest, Guido Guidotti's name might have appeared on many more of the textbook membrane protein discoveries of the 20th century. Trainees in his lab at Harvard Medical School unraveled the stoichiometry of the sodium-potassium ATPase; discovered that it, and a glucose transporter, are responsive to insulin; and explored cell signaling responses to other hormones, such as vasopressin (1,2). But Guidotti was loath to claim credit for research from his lab if he had not conducted experiments himself.