Multi-wavelength femtosecond laser LIPSS generation on titanium alloy and comparative study of their effect on cell adhesions

Titanium based dental implant suffer sometimes from failure due to lack of osseointegration in the jaw bone. In this work, we study the generation of Laser Induced Periodic Structures (LIPSS) using three different femtosecond lasers with wavelengths of 1030,515 & 257nm. Fully covered Titanium alloy (Ti6AlV) samples with different LIPSS periodicities are produced and wettability tests are performed prior and post sterilization of the samples. Finally, a comparison between the effect of different LIPSS on the cell adhesion is performed using mesenchymal stem cells to identify the best pattern for enhanced cell adhesion.