3D-printing of oxidized starch-based hydrogels with superior hydration properties

High-hydration hydrogels based on carbohydrate polymers and green preparation methods have attracted intensive research focus recently. Driven by the attractive functions of starch, oxidized maize starch (OMS) was chosen and the related hydrogel (3D-OMS) was constructed by hot-extrusion 3D printing (HE-3DP). Meanwhile, the effect of different OMS concentrations (11 %–19 %) on its printability, structure and hydration properties were systematically investigated. The results showed that the formation of porous structure during HE-3DP environment contributed to rapid water absorption and well water holding capacity of 3D-OMS. Interestingly, as the OMS concentration increased from 11 % to 19 %, the 3D-OMS presented great hydration properties, with its maximum water absorption capacity and water holding capacity reaching 3013.43 % (11-OMS) and 93.53 % (19-OMS), respectively. Among them, 13 % was the best concentration for HE-3DP. Besides, 3D-OMS also exhibited good biodegradability and cytocompatibility. These results demonstrated potential for developing new starch-based biomedical hydrogel with great hydration properties through HE-3DP technology.