Computational modeling and druggability assessment of Aggregatibacter actinomycetemcomitans leukotoxin

Mohammed Hakmi,El Mehdi Bouricha,Jaouad El Harti,Said Amzazi,Lahcen Belyamani, Jamal Eddine Khanfri,Azeddine Ibrahimi

Computer Methods and Programs in Biomedicine（2022）

引用 0|浏览1

暂无评分

摘要

•LtxA of Aggregatibacter actinomycetemcomitans plays an important role in immune system evasion•The lack of a tertiary structure of LtxA limits its understanding at the molecular level•The elucidation of the structural model of LtxA could open new avenues for the discovery of novel leads to disrupt its activity

查看译文

关键词

Aggregatibacter,Leukotoxin,LtxA,Modeling,Molecular dynamics,Druggability

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要