TFIIIC-based chromatin insulators through eukaryotic evolution

Rebecca E Sizer, Nisreen Chahid, Sienna P Butterfield,David Donze,Nia J Bryant,Robert J White

Gene（2022）

引用 0|浏览10

暂无评分

摘要

•Insulator activity is demonstrated for Pichia pastoris tRNA genes (tDNAs)•Epigenetic features of human tDNA insulators investigated bioinformatically.•Histone acetyltransferase p300 found at hundreds of tDNAs in human cells.•Hundreds of tDNAs associate with insulator proteins USF1 and CTCF in human cells.•Model proposed based around TFIIIC to explain insulator activities of human tDNAs.

查看译文

关键词

CTCF,ETC,HAT,HMR,pol,Sir,tDNA,TFIIIC,TFIIIB,TAD,USF

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要