p53 Directly Downregulates the Expression of CDC20 to Exert Anti-Tumor Activity in Mantle Cell Lymphoma

Yingtong Chen,Ping Yang,Jing Wang,Mingxia Zhu,Yanfang Wang,Shuang Gao,Weilong Zhang,Xiaoyan Ke,Hongmei Jing

Social Science Research Network（2022）

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摘要

Our study validates the essential role of p53 and CDC20 in MCL tumorigenesis, and provides a new insight for MCL therapeutics through dual-targeting p53 and CDC20.

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关键词

Apoptosis,CDC20,Mantle cell lymphoma,Proliferation,p53

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