Determining patterns of vascular function and structure in wild-type transthyretin cardiac amyloidosis. A comparative study

Kimon Stamatelopoulos, Dimitrios Delialis,Georgios Georgiopoulos, Maria-Irini Tselegkidi, Foteini Theodorakakou,Ioanna Dialoupi, Dimitrios Bambatsias,Ioannis Petropoulos, Giuseppe Vergaro,Ignatios Ikonomidis, Stavros Tzortzis,Alexandros Briasoulis, John Kanakakis,Ioannis Trougakos, Meletios A. Dimopoulos,Efstathios Kastritis

International Journal of Cardiology（2022）

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摘要

•ATTRwt is not associated with accelerated vascular aging or subclinical atherosclerosis•ATTRwt patients present a preserved peripheral vascular fingerprint in comparison to HFpEF and cardiac AL•ATTRwt vascular fingerprint consists of lower blood pressure and preserved arterial wave reflections and FMD•Arterial wave reflections and FMD discriminate ATTRwt from cardiac AL and HFpEF beyond established cardiac biomarkers

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