Multi-stage transcriptome profiling of the neglected food-borne echinostome Artyfechinostomum sufrartyfex reveal potential diagnostic and drug targets

Acta Tropica(2022)

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摘要
•Transcriptome analysis revealed 14 diagnostic markers for A. sufrartyfex detection.•Unique epitopes identified for 10 out of the 14 diagnostic markers.•Antioxidants, proteases among the important diagnostic candidates.•10 potential candidates out of 145 shortlisted as drug targets.•FDA-approved and ZINC molecules identified for the potential drug targets.
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关键词
Echinostomiasis,Artyfechinostomum sufrartyfex,Transcriptome,Secretome,Diagnostic targets,Drug targets
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