Disparities in positive results and dissemination of randomized controlled trials in immuno-oncology.

Cheng Xu,Shu Zhang,Guang-Li Zhu,Kai-Bin Yang,Yuan Zhang,Yan-Ping Mao,Ling-Long Tang,Qing Liu,Ying Huang,Jun Ma

International reviews of immunology（2023）

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摘要

Disparities in positive result dissemination are widespread in IO RCTs and affected by trial features. We proposed improvements in upfront registration, procedural integrity, and adequate inclusion of rival trials reporting negative results within the earlier two years in future reviews.

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关键词

Immuno-oncology,immunotherapy,positive result,publication,randomized controlled trial

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