A Model of Pupillometric Signals for Studying Inherited Retinal Diseases in Childhood Population

A cutting-edge method to assess the status of photoreceptors is represented by chromatic pupillometry, which consists in stimulating the eyes of the patients with light of different wavelengths and intensities. The signals of the dynamics of the pupil after the optical stimulations can be approximated by a 2nd-order linear model. Fitting parameters are established by a weighted least-squares algorithm, in order to achieve the correct estimate of the shape of the pupillometric data. Results presented in this work indicate that our model is able to capture the dynamics of pupillometric signals.