Chronic CD27-CD70 Costimulation Promotes Type 1-Specific Polarization of Effector Tregs

Natalia Bowakim Anta,Valérie Acolty,Abdulkader Azouz,Guillaume Oldenhove,Hideo Yagita,Oberdan Leo,Stanislas Goriely,Muriel Moser

SSRN Electronic Journal（2021）

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摘要

We conclude that CD27 may regulate the development of Th1 immunity in peripheral tissues as well as the subsequent switch of the effector response into long-term memory.

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关键词

CD27 costimulation,CXCR3,dendritic cells,eomes,regulatory T cells

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