A mitochondrial-targeting iridium(iii) complex for H2O2-responsive and oxidative stress amplified two-photon photodynamic therapy

Inorganic Chemistry Frontiers(2021)

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摘要
The mitochondrial-targeting iridium(iii) complex Ir–B(OH)2 is activated in the presence of endogenous H2O2 to release the two-photon photosensitizer Ir–OH and the GSH scavenger methylquinone for amplified two-photon photodynamic therapy.
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