Effect of parasitic infestation on carpal synovial constituents in donkeys (Equus asinus)

The present study was carried out to examine the physical, microscopical and biochemical parameters of the synovial fluid from the carpal joints of donkeys suffering from Strongylus spp. and Parascaris equorum infestation. Forty-five donkeys were selected out from a total of sixty animals based on faecal analysis. Animals were divided into 3 groups, which included Strongylus spp. (n=23), mixed infestation (n=17, Strongylus spp. and Parascaris equorum) and control (n=5) groups. The aspirated synovial fluid from all animals (n=45) was examined physically and microscopically. Then, the total protein, albumin, globulins, calcium, phosphorus, magnesium, glucose levels, and gamma glutamyl transferase (GGT) and alkaline phosphatase (ALP) activities were measured in the serum and synovial fluid of all animals. The results revealed no changes of the physical and microscopical features of the synovial fluid of the infested and control animals but there were significant decreases in total protein, albumin, globulin, glucose and magnesium levels in the serum of Strongylus and mixed infection groups. The synovial fluid analysis exhibited an increase of calcium and phosphorus levels, and ALP activity, and decreased levels of total protein, glucose and GGT in Strongylus and mixed groups. The results of this study suggested significant changes in some biochemical parameters in both serum and synovial fluids in donkeys suffering from parasitic infestation.