One-step, kit-based radiopharmaceuticals for molecular SPECT imaging: a versatile diphosphine chelator for ^99mTc radiolabelling of peptides

Ingebjørg N. Hungnes,Fahad Al-Salemee,Peter J. Gawne,Thomas Eykyn,R. Andrew Atkinson,Samantha Y. A. Terry,Fiona Clarke,Philip J. Blower,Paul G. Pringle,Michelle T. Ma

Dalton Transactions（2021）

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摘要

We report a versatile diphosphine platform for 99mTc radiolabelling of peptides. The diphosphine-peptide conjugate can be radiolabelled with 99mTc in a single step, and the new radiotracer is capable of receptor-targeted imaging of disease in vivo.

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molecular spect imaging,versatile diphosphine chelator,peptides,radiopharmaceuticals,one-step,kit-based

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One-step, kit-based radiopharmaceuticals for molecular SPECT imaging: a versatile diphosphine chelator for 99mTc radiolabelling of peptides

One-step, kit-based radiopharmaceuticals for molecular SPECT imaging: a versatile diphosphine chelator for ^99mTc radiolabelling of peptides