Biomarkers of thromboinflammation correlate to COVID-19 infection and admission status in emergency department patients

Julie Goswami,Taleen A. MacArthur,Meera Sridharan,Julie Tange, Andrew J. Kirmse,Kaitlin A. Lundell,Dong Chen,Matthew T. Auton,Tony Y. Chon,Ryan T. Hurt,Bradley R. Salonen,Ravindra Ganesh,Young M. Erben, Christopher P. Marquez,Jing-Fei Dong,Rosemary A. Kozar,Stephanie F. Heller,Erica A. Loomis,Andrea L. Johnstone,Kent R. Bailey

Thrombosis Update（2021）

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摘要

•COVID-19 associated coagulopathy remains an urgent clinical issue.•Optimal biomarkers for COVID-19-associated coagulopathy are unknown.•Thrombin generation and Von Willebrand Factor correlate to COVID-19 and admission status.•COVID-19 patients have longer initiation of thrombin generation than volunteers.

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关键词

COVID-19,Extracellular traps,Thrombin,Von Willebrand factor

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