A photo-thermal nanocomposite capable of relieving inflammatory response to compete multidrug-resistant pseudomonas aeruginosa infection

Qianqian Guo,Yongjun Luo,Honglei Guo,Tianyu Lan,Shengquan Wang,Kedui Geng,Xin Lu,Ling Tao,Xiangchun Shen

Chemical Engineering Journal（2022）

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摘要

•The nanocomposites could adhere bacteria via intetact with bacterial membrane.•AuNRs@PBArPEGMA could protect macrophages from P. aeruginosa infection.•The tissue penetration depth of AuNRs@PBArPEGMA + NIR was up to 12 nm in pork muscle.•AuNRs@PBArPEGMA could effectively treat P. aeruginosa lung infection.

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关键词

Drug-resistant bacteria,Pneumonia,Antibacterial activity,Photo-thermal therapy

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