Strategies to Account for Design Misspecifications in Randomized Controlled Trials.

Mortality rates of infants (younger than 1 year of age) and neonates (younger than 1 month of age) remain unacceptably high in some geographic regions.1,2 After the first week of life, infection is a significant cause of neonatal and postneonatal mortality.3,4 Biannual mass azithromycin administration has been shown to reduce all-cause childhood mortality by as much as 25% among infants 1 to 5 months of age in Niger.5.