Rectal lymphoma: a rare case report with review of literature

Introduction: Colorectal lymphoma is an extremely rare disease. The disease is usually diagnosed in the advanced stages because of its primary nonspecific symptoms. Treatment modality of primary lymphoma of the rectum remains uncertain. Case History: A 45-year-old male presented with rectal bleeding, pain in perianal region and alteration in bowel habits along with fungating and circumferential mass in the rectum. The histopathology and immunohistochemistry confirmed the diagnosis of Plasmablastic Lymphoma. He was planned six cycles of CHOP regime. On follow up the residual disease was managed with second line of chemotherapy (DHAP regimen). The patient was started on Metronomic chemotherapy (Chlorambucil & Etoposide) in view of persistent residual disease. Conclusion: Optimal treatment for rectal lymphoma needs to be established.