Database of Active Pharmaceutical Ingredients (APIs) present in the Brazilian Pharmacopeia

Active Pharmaceutical Ingredients (APIs) are molecules that can be used for the manufacturing of Drugs. The Brazilian Health Regulatory Agency (Agência Nacional de Vigilância Sanitária) is responsible for the oversight and approval of production and distribution of all drugs in Brazilian territory. Four different databases, including 336 out of the 346 total APIs, were created from the APIs text information available in the 6th edition of the Brazilian pharmacopeia, volume 2, “Active Pharmaceutical Ingredients” monography. Each database is composed by a different extension file, they are: two-dimensional sdf, three-dimensional sdf, mol2 and PDBQT file extensions, converted by using OpenBabel and Marvin Sketch software.