Copper-catalyzed alkylation of Quinoxalin-2(1H) - ones with styrenes and tert-Butyl peroxybenzoate

Xiaoyang Zhong, Xin Ying Li,Hua Yao,Yan Zhaohua, Hui Guo, Li Min,Lin Sen

Synlett（2022）

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摘要

A simple strategy for the synthesis of 3-substituted Quinoxalin-2(1H)-ones containing ether units is proposed. The method is realized by the three-component synthesis of Quinoxalin-2(1H)-ones, styrenes and tert-Butyl peroxybenzoate (TBPB). This reaction has good functional group tolerance and may involve a free radical process.

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关键词

quinoxalin-2(1H )-ones, three-component synthesis, styrenes, free radicals

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