Lack of Clinical Relevance of Bilastine-Food Interaction in Healthy Volunteers: A Wheal and Flare Study.

Jimena Coimbra,Montserrat Puntes,Ignasi Gich,Joan Martínez, Pol Molina,Rosa Antonijoan,Cristina Campo,Luis Labeaga

International archives of allergy and immunology（2022）

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摘要

The pharmacokinetic interaction of bilastine with food does not imply a significant reduction of its peripheral antihistaminic efficacy. Despite a slight delay in onset of action on the first treatment day, the global clinical efficacy of bilastine is not affected by coadministration with food.

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关键词

Antihistaminic effect,Bilastine,Food interaction,Pharmacodynamics,Pharmacokinetics

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