Macrophage-derived MLKL in alcohol-associated liver disease: regulation of phagocytosis in hepatic macrophages

X. Q. Wu,X. D. Fan,M. R. McMullen,T. Miyata,A. Kim, V. Pathak,J. G. Wu,N. Welch,J. Dasarathy,D. S. Allende,A. J. McCullough,D. M. Rotroff,S. Dasarathy,L. E. Nagy

Hepatology (Baltimore, Md.)（2022）

引用 6|浏览22

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摘要

Together, these data indicate that myeloid MLKL restricts ethanol-induced liver inflammation and injury by regulating hepatic immune cell homeostasis and macrophage phagocytosis.

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关键词

liver disease,macrophage‐derived,mlkl,alcohol‐associated

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