Phage Therapy of Mycobacterium Infections: Compassionate Use of Phages in 20 Patients With Drug-Resistant Mycobacterial Disease.

Rebekah M Dedrick,Bailey E Smith,Madison Cristinziano,Krista G Freeman,Deborah Jacobs-Sera,Yvonne Belessis,A Whitney Brown,Keira A Cohen,Rebecca M Davidson,David van Duin, Andrew Gainey, Cristina Berastegui Garcia, C R Robert George,Ghady Haidar,Winnie Ip,Jonathan Iredell,Ameneh Khatami,Jessica S Little, Kirsi Malmivaara,Brendan J McMullan,David E Michalik,Andrea Moscatelli,Jerry A Nick, Maria G Tupayachi Ortiz,Hari M Polenakovik,Paul D Robinson,Mikael Skurnik,Daniel A Solomon,James Soothill,Helen Spencer,Peter Wark,Austen Worth,Robert T Schooley,Constance A Benson,Graham F Hatfull

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America（2023）

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摘要

Phage treatment of Mycobacterium infections is challenging due to the limited repertoire of therapeutically useful phages, but favorable clinical outcomes in patients lacking any other treatment options support continued development of adjunctive phage therapy for some mycobacterial infections.

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关键词

mycobacteriophage,nontuberculous mycobacteria,phage therapy

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