Soluble Urokinase-Type Plasminogen Activator Receptor as a Prognostic Marker of Ugandan Children at Risk of Severe and Fatal Malaria.

Veselina Stefanova,Michelle Ngai,Andrea M Weckman,Julie K Wright,Kathleen Zhong,Melissa Richard-Greenblatt,Chloe R McDonald,Andrea L Conroy,Sophie Namasopo,Robert O Opoka,Michael Hawkes,Kevin C Kain

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America（2023）

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摘要

Measuring suPAR at presentation can identify children at risk of severe and fatal malaria. Adding suPAR to clinical scores could improve the recognition and triage of children at risk of death. suPAR can be detected with a point-of-care test and can now be evaluated in prospective trials.

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关键词

mortality outcome,prognostic marker,risk-stratification,severe malaria,soluble urokinase-type plasminogen activator receptor

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