Design and Rationale for the Treating Obstructive Sleep Apnea Using Targeted Hypoglossal Nerve Stimulation (OSPREY) Trial
Contemporary Clinical Trials(2022)
摘要
Obstructive sleep apnea (OSA) affects nearly 1 billion people worldwide, including approximately 35 million US residents. OSA has detrimental cardiovascular and neurocognitive consequences. Positive airway pressure corrects sleep disordered breathing but is not always tolerated or used sufficiently. Oral appliances and surgery provide alternatives in select populations but are variably effective.
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关键词
Obstructive sleep apnea,Randomized,Controlled trial,Adaptive design,Surgical treatment,Hypoglossal nerve,Targeted hypoglossal nerve stimulation,Neurostimulation,Sleep
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