Metal-Organic Compounds as Anticancer Agents: Versatile Building Blocks for Selective Action on G-quadruplexes.

Patricia M Toro,Marianela Saldias,Gabriela Valenzuela-Barra

Current medicinal chemistry（2023）

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摘要

This stabilization can be achieved through extended square aromatic surfaces, increased hydrophobicity, different auxiliary ligands, axially coordinated ligands, and the nature of the metal center.

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关键词

Cancer therapy,G-quadruplex,G4-ligands,metallo-compounds,oncogene promoters,telomerase

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