A Wolf in Sheep's Clothing: Systemic Immune Activation Post Immunotherapy.

Crescens Tiu,Rajiv Shinde,Abhijit Pal,Andrea Biondo,Alex Lee,Nina Tunariu,Shaman Jhanji,Vimal Grover,Kate Tatham,Pascale Gruber,Udai Banerji, Johann S De Bono,Emma Nicholson,Anna R Minchom,Juanita S Lopez

Journal of immunotherapy and precision oncology（2021）

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摘要

SIA/HLH post ICI is a rare but a potentially fatal irAE that presents with fever and a constellation of nonspecific symptoms. Early recognition and timely treatment are key to improving outcomes.

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关键词

HLH,fever,immune checkpoint inhibitor,immune-related adverse events,systemic immune activation,toxicity

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