PHACTR1 modulates vascular compliance but not endothelial function: a translational study.

Alice Wood,Alexios Antonopoulos,Surawee Chuaiphichai,Theodosios Kyriakou,Rebeca Diaz,Abtehale Al Hussaini,Anna-Marie Marsh,Manjit Sian, Mitul Meisuria,Gerry McCann,Victoria S Rashbrook,Edward Drydale, Sally Draycott,Murray David Polkinghorne,Ioannis Akoumianakis,Charalambos Antoniades,Hugh Watkins,Keith M Channon,David Adlam,Gillian Douglas

Cardiovascular research（2023）

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摘要

In conclusion, we have shown a role for PHACTR1 in arterial compliance across multiple vascular beds. Our study suggests that PHACTR1 has a key structural role within the vasculature.

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关键词

PHACTR1 ,Arteries,Compliance,Endothelial cells

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