879 Reversal of lactate and PD-1-mediated macrophage immunosuppression controls growth of PTEN/p53-deficient prostate cancer

Clinical cancer research : an official journal of the American Association for Cancer Research(2022)

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摘要
Immunometabolic strategies that reverse lactate and PD-1-mediated TAM immunosuppression, in combination with ADT, warrant further investigation in PTEN-deficient mCRPC patients.
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关键词
macrophage immunosuppression controls growth,prostate cancer,lactate
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