Genome-wide association studies on Northern Italy isolated populations provide further support concerning genetic susceptibility for major depressive disorder.

Vincenzo Dattilo,Sheila Ulivi,Alessandra Minelli,Martina La Bianca,Edoardo Giacopuzzi,Marco Bortolomasi,Stefano Bignotti,Massimo Gennarelli,Paolo Gasparini,Maria Pina Concas

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry（2023）

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摘要

Our work suggests new possible genes associated with MDD, and the PRS analysis confirms the polygenic nature of this disorder. Future studies are required to better understand the role of these findings in MDD.

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关键词

CTNNA2,KCNQ5,Major depressive disorder,genetic isolates,genome-wide association study

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