Immune checkpoint inhibitor toxicity and associated outcomes in older patients with cancer

Yacki Hayashi-Tanner,Peter J Polewski,Mamatha Gaddam,Nancy R Fisher,Attila J Kovacs,David E Marinier

Journal of Geriatric Oncology（2022）

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摘要

The irAE prevalence in older patients was similar to that in younger patients. To our knowledge, this is one of few studies that confirms a positive association of irAE on both OS and PFS in older patients with cancer, and improved OS and PFS with lower versus higher grade irAE.

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关键词

Immune checkpoint inhibitors,Immune checkpoint inhibitors/adverse effects,Immunotherapy,Geriatric oncology

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