The use of a chimeric antigen for Plasmodium falciparum and P. vivax seroprevalence estimates from community surveys in Ethiopia and Costa Rica.

Jessica N McCaffery,Balwan Singh,Douglas Nace,Ashenafi Assefa,Jimee Hwang,Mateusz Plucinski,Nidia Calvo,Alberto Moreno,Venkatachalam Udhayakumar,Eric Rogier

PloS one（2022）

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摘要

Our data indicate that chimeric antigen PvRMC-MSP1 is able to capture antibodies to multiple epitopes from both prior P. falciparum and P. vivax infections, and suitable chimeric antigens can be considered for use in serosurveys with appropriate validation.

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