Facilely self-assembled and dual-molecule calibration aptasensor based on SERS for ultra-sensitive detection of tetrodotoxin in pufferfish

Lijun Yin,Min Fan,Qiutian She,Ruiyun You,Yudong Lu,Dechan Lu, Minlin Li

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy（2022）

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摘要

•A sensitive and efficient method of TTX quantitative detection based on SERS was established.•The self-assembled and dual-molecule calibration aptasensor prepared by this method has an excellent uniformity (RSD = 8.8%).•The detection linearrange of the aptasensor was 0.0319–319.27 ng/mL, with a limit of detection (LOD) of 0.024 ng/mL, achieving recoveries ranging from 95.75% to 99%.

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关键词

Raman spectroscopy,Tetrodotoxin(TTX),Aptasensor,Quantitative detection,Food safety

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