Multicomponent Synthesis of Pyrano (3, 2-c) Quinolone Fused Spirochromenes

POLYCYCLIC AROMATIC COMPOUNDS(2023)

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摘要
A multicomponent pathway has been described for the synthesis of novel pyrano (3,2-c) quinolone fused spirochromenes by piperidine catalyzed reaction between isatins, phenyl (or alkyl) sulfonyl acetonitrile and 4-hydroxy-N-methylquinoline-2-one. Decent yields coupled with easy isolation of the products and avoidance of conventional purification methods are the noteworthy merits of the developed protocol.
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关键词
4-hydroxy-N- methylquinolin-2-one, Isatin, phenylsulfonyl acetonitrile, piperidine, multicomponent reactions, spirochromenes
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